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CONCLUSION. As indicated by widespread adoption, ChEBI has become an essential bioinformatics chemistry database, enabling multiple diverse applications for different types of user in various scientific contexts.


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The Gene Ontology (GO) facilitates the description of the action of gene products in a biological context. Many GO terms refer to chemical entities that participate in biological processes. To facilitate accurate and consistent systems-wide biological representation, it is necessary to integrate the chemical view of these entities with the biological view of GO functions and processes.


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INTRODUCTION. Chemical Entities of Biological Interest (ChEBI) is a database and ontology for low-molecular-weight chemical entities that are relevant for understanding and intervening in biological functioning (1,2).The core information ChEBI provides is a stable and unique ChEBI identifier along with a name, chemical structure and ontological classification.


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Background ChEBI is a database and ontology of chemical entities of biological interest. It is widely used as a source of identifiers to facilitate unambiguous reference to chemical entities within biological models, databases, ontologies and literature. ChEBI contains a wealth of chemical data, covering over 46,500 distinct chemical entities, and related data such as chemical formula, charge.


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A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity. cofactor. An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). (via porphyrins )


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OntoBee AberOWL OLS CHEBI Bioregistry A freely available dictionary of molecular entities focused on 'small' chemical compounds. The term 'molecular entity' refers to any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity.

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